Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 5/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21545848 | 1.00 | ACLY (0.39) | ACLYSLC40A1POLBCCR2PTGES2 | |
| SCHEMBL20354703 | 0.82 | ACLY (0.34) | ACLYSLC40A1 | |
| SCHEMBL30286458 | 0.82 | ACLY (0.34) | ACLYSLC40A1 | |
| SCHEMBL20340304 | 0.81 | PTGES2 (0.41) | ACLYPTGES2 | |
| SCHEMBL20340324 | 0.80 | ACLY (0.43) | ACLYPTGES2SMN1; SMN2 | |
| SCHEMBL20340724 | 0.77 | SLC6A4 (0.40) | ACLYSLC40A1POLBCCR2PTGES2 | |
| SCHEMBL20355299 | 0.77 | SLC40A1 (0.49) | SLC40A1 | |
| SCHEMBL30286375 | 0.77 | SLC40A1 (0.49) | SLC40A1 | |
| SCHEMBL20355177 | 0.77 | ACLY (0.42) | ACLYSLC40A1CCR2PTGES2 | |
| SCHEMBL30286537 | 0.77 | ACLY (0.42) | ACLYSLC40A1CCR2PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |