Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.44 |
| ▸ | SGK1 | O00141 | 6/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | CCR4 | P51679 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354726 | 1.00 | SLC40A1 (0.44) | SLC40A1SGK1CCR2CYP2C19POLB | |
| SCHEMBL20355182 | 0.91 | CCR2 (0.41) | SLC40A1SGK1CCR2CYP2C19KIT | |
| SCHEMBL20344344 | 0.89 | SLC40A1 (0.39) | SLC40A1SGK1CYP2C19KITCCR4 | |
| SCHEMBL30286487 | 0.89 | SCN9A (0.42) | SLC40A1SGK1CCR2CYP2C19CCR4 | |
| SCHEMBL21545847 | 0.89 | SCN9A (0.42) | SLC40A1SGK1CCR2CYP2C19CCR4 | |
| SCHEMBL20355390 | 0.87 | CCR4 (0.39) | SLC40A1SGK1CCR2CYP2C19CCR4 | |
| SCHEMBL29560319 | 0.87 | CCR4 (0.39) | SLC40A1SGK1CCR2CYP2C19CCR4 | |
| SCHEMBL21545927 | 0.85 | POLB (0.46) | SGK1POLBALPLLMNAHTT | |
| SCHEMBL26776822 | 0.85 | CCR4 (0.42) | CCR4NR4A2ALPLLMNA | |
| SCHEMBL30286565 | 0.85 | POLB (0.46) | SGK1POLBALPLLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |