Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.39 |
| ▸ | CCR4 | P51679 | 2/20 | 0.36 |
| ▸ | SGK1 | O00141 | 7/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30286657 | 0.91 | TDO2 (0.37) | SLC40A1CCR4SGK1TDO2ALPL | |
| SCHEMBL21545940 | 0.91 | TDO2 (0.37) | SLC40A1CCR4SGK1TDO2ALPL | |
| SCHEMBL20354726 | 0.89 | SLC40A1 (0.44) | SLC40A1CCR4SGK1KITCYP2C19 | |
| SCHEMBL30286500 | 0.89 | SLC40A1 (0.44) | SLC40A1CCR4SGK1KITCYP2C19 | |
| SCHEMBL20339198 | 0.81 | SGK1 (0.39) | SLC40A1SGK1KITTDO2 | |
| SCHEMBL20355182 | 0.81 | CCR2 (0.41) | SLC40A1CCR4SGK1KITCYP2C19 | |
| SCHEMBL21545847 | 0.79 | SCN9A (0.42) | SLC40A1CCR4SGK1CYP2C19TDO2 | |
| SCHEMBL20354864 | 0.79 | TDO2 (0.39) | SLC40A1CCR4SGK1TDO2ALPL | |
| SCHEMBL30286487 | 0.79 | SCN9A (0.42) | SLC40A1CCR4SGK1CYP2C19TDO2 | |
| SCHEMBL20355390 | 0.77 | CCR4 (0.39) | SLC40A1CCR4SGK1CYP2C19TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562820-A1 | (AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES | UCB Pharma GmbH (DE) | 2019-11-06 | — | — | EP | claimed |
| WO-2018122232-A1 | (AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES | UCB PHARMA GMBH (DE) | 2018-07-05 | — | — | WO | claimed |
| EP-3562820-A1 | (AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES | UCB Pharma GmbH (DE) | 2019-11-06 | — | — | EP | disclosed |
| WO-2018122232-A1 | (AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES | UCB PHARMA GMBH (DE) | 2018-07-05 | — | — | WO | disclosed |