Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 5/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 2/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339151 | 1.00 | CCR4 (0.45) | CCR4KAT6ANR4A2ALPLMEN1 | |
| SCHEMBL20354911 | 0.87 | CCR4 (0.39) | CCR4NR4A2ALPLSGK1 | |
| SCHEMBL30286436 | 0.87 | CCR4 (0.39) | CCR4NR4A2ALPLSGK1 | |
| SCHEMBL20339186 | 0.84 | CCR4 (0.46) | CCR4KAT6ANR4A2ALPLMEN1 | |
| SCHEMBL30286576 | 0.84 | CCR4 (0.46) | CCR4KAT6ANR4A2ALPLMEN1 | |
| SCHEMBL20340328 | 0.83 | HTR6 (0.37) | CCR4KAT6ANR4A2ALPLMEN1 | |
| SCHEMBL27053565 | 0.82 | CCR4 (0.45) | CCR4KAT6ANR4A2SGK1 | |
| SCHEMBL20339134 | 0.82 | LMNA (0.45) | CCR4KAT6ANR4A2ALPLMEN1 | |
| SCHEMBL20354845 | 0.81 | CCR4 (0.42) | CCR4KAT6ANR4A2ALPLMEN1 | |
| SCHEMBL26776822 | 0.81 | CCR4 (0.42) | CCR4KAT6ANR4A2ALPLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |