Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 2/20 | 0.39 |
| ▸ | SGK1 | O00141 | 12/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SGK3 | Q96BR1 | 1/20 | 0.34 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354911 | 1.00 | CCR4 (0.39) | CCR4SGK1ALPLCCR2TDO2 | |
| SCHEMBL20354864 | 0.89 | TDO2 (0.39) | CCR4SGK1ALPLCCR2TDO2 | |
| SCHEMBL20355181 | 0.87 | CCR2 (0.39) | CCR4SGK1CCR2TDO2NR4A2 | |
| SCHEMBL30286556 | 0.87 | CCR4 (0.45) | CCR4SGK1ALPLNR4A2 | |
| SCHEMBL27053565 | 0.87 | CCR4 (0.45) | CCR4SGK1CCR2NR4A2 | |
| SCHEMBL20339151 | 0.87 | CCR4 (0.45) | CCR4SGK1ALPLNR4A2 | |
| SCHEMBL20354925 | 0.85 | SGK1 (0.36) | SGK1ALPLCCR2TDO2NR4A2 | |
| SCHEMBL21545889 | 0.85 | TDO2 (0.39) | CCR4SGK1CCR2TDO2NR4A2 | |
| SCHEMBL30286554 | 0.85 | TDO2 (0.39) | CCR4SGK1CCR2TDO2NR4A2 | |
| SCHEMBL29560319 | 0.85 | CCR4 (0.39) | CCR4SGK1ALPLCCR2TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |