Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354811 | 0.92 | HTR2C (0.41) | PARP10SCN9AHTR2AHTR2CHTR2B | |
| SCHEMBL23914594 | 0.83 | HTR2C (0.42) | PARP10CDK2HTR2AHTR2CHTR2B | |
| SCHEMBL24180204 | 0.80 | HTR2C (0.42) | PARP10CDK2SCN9AHTR2AHTR2C | |
| SCHEMBL30780907 | 0.77 | SCN9A (0.46) | SCN9ASCN5A | |
| SCHEMBL22069559 | 0.77 | PARP10 (0.45) | PARP10CDK2MCHR1HTR2AHTR2C | |
| SCHEMBL27267930 | 0.77 | SCN9A (0.46) | SCN9ASCN5A | |
| SCHEMBL12261484 | 0.77 | MCHR1 (0.49) | PARP10CDK2MCHR1HTR2AHTR2C | |
| SCHEMBL24180164 | 0.75 | PARP10 (0.43) | PARP10CDK2SCN9AMCHR1SCN5A | |
| SCHEMBL30286630 | 0.75 | CYP19A1 (0.48) | PARP10CDK2SCN9ASCN5AHTR2A | |
| SCHEMBL9873759 | 0.74 | FFAR4 (0.44) | SCN9AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |