SCHEMBL30288196

SCHEMBL30288196

COc1c(C(C)(C)C)cc2c(c1-c1cc(C)cc(C)c1)C=C(C)C2[SiH](C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.30
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14645969 0.86 PDE4B (0.37)
SCHEMBL22863127 0.86 CNR2 (0.32) PTGS2PTGS1
SCHEMBL28353730 0.85
Hydrochloric Acid SCHEMBL30396833 0.84 CNR2 (0.31)
Hydrochloric Acid SCHEMBL28495051 0.84
SCHEMBL20165773 0.83
SCHEMBL20165779 0.82 PTGS2 (0.32) PTGS2PTGS1
SCHEMBL21451161 0.82 PTGS1 (0.32) PTGS2PTGS1
SCHEMBL29874052 0.82 PTGS2 (0.32) PTGS2PTGS1
SCHEMBL28759366 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112292406-B Olefin polymerization catalyst 博里利斯股份公司 2023-04-04 CN disclosed