Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 10/20 | 0.46 |
| ▸ | HTR2C | P28335 | 10/20 | 0.46 |
| ▸ | DRD2 | P14416 | 9/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25298382 | 0.83 | HTR6 (0.69) | HTR6HTR2AHTR2CDRD2CYP3A4 | |
| SCHEMBL30288467 | 0.82 | HTR6 (0.48) | HTR6HTR2AHTR2CDRD2CRHBP | |
| SCHEMBL30288465 | 0.80 | HTR2A (0.67) | HTR6HTR2AHTR2CDRD2CYP3A4 | |
| SCHEMBL24243704 | 0.79 | HTR2A (0.69) | HTR6HTR2AHTR2CDRD2CYP3A4 | |
| SCHEMBL24243756 | 0.77 | HTR2A (0.58) | HTR6HTR2AHTR2CDRD2TSHR | |
| SCHEMBL30288463 | 0.76 | HTR6 (0.44) | HTR6HTR2AHTR2CDRD2CHRNB2 | |
| SCHEMBL30288464 | 0.74 | MAPT (0.45) | HTR6HTR2AHTR2CDRD2CHRNB2 | |
| SCHEMBL30288449 | 0.74 | MAPT (0.45) | HTR6HTR2AHTR2CDRD2CHRNB2 | |
| SCHEMBL30288451 | 0.74 | CHRNB2 (0.46) | HTR6CHRNB2CHRNA7CHRNA4KDM4E | |
| SCHEMBL30288454 | 0.74 | CHRNB2 (0.46) | HTR6CHRNB2CHRNA7CHRNA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146198-A1 | NOVEL COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | Psilera Inc. (US) | 2023-03-15 | — | — | EP | claimed |
| EP-4146198-A1 | NOVEL COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | Psilera Inc. (US) | 2023-03-15 | — | — | EP | disclosed |