Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 11/20 | 0.42 |
| ▸ | HTR2C | P28335 | 11/20 | 0.42 |
| ▸ | DRD2 | P14416 | 9/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25298382 | 0.80 | HTR6 (0.69) | HTR6HTR2AHTR2CDRD2HTR1A | |
| SCHEMBL30288465 | 0.77 | HTR2A (0.67) | HTR6HTR2AHTR2CDRD2HTR1A | |
| SCHEMBL30288455 | 0.76 | HTR6 (0.48) | HTR6HTR2AHTR2CDRD2HTR1A | |
| SCHEMBL24243704 | 0.76 | HTR2A (0.69) | HTR6HTR2AHTR2CDRD2HTR1A | |
| SCHEMBL27962585 | 0.74 | HTR6 (0.49) | HTR6HTR2AHTR2CDRD2HTR1D | |
| SCHEMBL24243756 | 0.74 | HTR2A (0.58) | HTR6HTR2AHTR2CDRD2HTR1A | |
| Hydrochloric Acid SCHEMBL31535656 | 0.72 | HTR6 (0.48) | HTR6HTR2AHTR2CDRD2HTR1D | |
| SCHEMBL31664938 | 0.71 | CHRNB2 (0.37) | HTR6HTR2AHTR2CDRD2CHRNB2 | |
| SCHEMBL31696757 | 0.71 | ALDH1A1 (0.46) | HTR6HTR2AHTR2CDRD2CYP3A4 | |
| SCHEMBL28190374 | 0.67 | EGFR (0.68) | ADRA1ASLC6A3MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146198-A1 | NOVEL COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | Psilera Inc. (US) | 2023-03-15 | — | — | EP | claimed |
| EP-4146198-A1 | NOVEL COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | Psilera Inc. (US) | 2023-03-15 | — | — | EP | disclosed |