Malonic Acid

Malonic Acid

SCHEMBL30288586

CC(CO)CO.O=C(O)CC(=O)O

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.53
SRR Q9GZT4 1/20 0.53
TSHR P16473 3/20 0.39
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
PTGS2 P35354 1/20 0.36
FFAR3 O14843 1/20 0.35
OR51E2 Q9H255 1/20 0.35
GABRP O00591 2/20 0.35
GABRD O14764 2/20 0.35
GABRA1 P14867 2/20 0.35
GABRB1 P18505 2/20 0.35
GABRG2 P18507 2/20 0.35
GABRB3 P28472 2/20 0.35
GABRA5 P31644 2/20 0.35
GABRA3 P34903 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetoacetic Acid SCHEMBL2705262 0.87 KDM4E (0.41) LDHASRRTSHRCYP2D6CYP2C19
Malonic Acid SCHEMBL28265925 0.85 LDHA (0.56) LDHASRRTSHRCYP2D6CYP2C19
Bicarbonate SCHEMBL6933680 0.84 TSHR (0.45) TSHRCYP2D6CYP2C19TDP1OR51E2
Malonic Acid SCHEMBL11880083 0.82 TDP1 (0.59) LDHASRRTSHRCYP2D6CYP2C19
Succinic Acid SCHEMBL18691126 0.82 LMNA (0.53) TSHRLMNAFFAR3OR51E2GABRP
Propionic Acid SCHEMBL9756910 0.82 FFAR3 (0.59) TSHRTDP1ALDH1A1FFAR3OR51E2
Acetic Acid SCHEMBL9756915 0.81 FFAR3 (0.47) TSHRTDP1ALDH1A1FFAR3OR51E2
Malonic Acid SCHEMBL30288576 0.81 TSHR (0.41) LDHASRRTSHRTDP1MAPT
Thioglycolic Acid SCHEMBL32681731 0.80 TSHR (0.38) TSHRTDP1ALDH1A1LMNAMAPT
Adipic Acid SCHEMBL31157623 0.78 LMNA (0.58) TSHRTDP1ALDH1A1LMNAOR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109791381-B Electrophotographic photoreceptor, and electrophotographic process cartridge and image forming apparatus containing the same 三菱化学株式会社 2023-03-10 CN disclosed