Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289608 | 0.91 | MEN1 (0.43) | CYP1A2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL30289633 | 0.91 | CETP (0.37) | CYP1A2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL30289586 | 0.89 | LPAR1 (0.44) | CYP1A2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL30289703 | 0.86 | MEN1 (0.39) | CYP1A2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL30289595 | 0.83 | LPAR1 (0.38) | CYP1A2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL30367508 | 0.82 | LMNA (0.42) | KMT2AMEN1NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30289624 | 0.81 | CETP (0.37) | CYP1A2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL30289642 | 0.73 | ABL1 (0.61) | CYP1A2CYP3A4KMT2AKDM4EMEN1 | |
| SCHEMBL30289701 | 0.69 | LMNA (0.44) | CYP1A2CYP3A4KMT2AMEN1CYP2D6 | |
| SCHEMBL19878173 | 0.66 | GAA (0.44) | KMT2AKDM4EMEN1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894497-A | Imidazopyrimidine compounds, and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |