Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 4/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | MST1R | Q04912 | 2/20 | 0.34 |
| ▸ | HGF | P14210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289586 | 0.90 | LPAR1 (0.44) | LPAR1LPAR5CYP19A1MEN1ALDH1A1 | |
| SCHEMBL30289608 | 0.88 | MEN1 (0.43) | CYP19A1MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL30289624 | 0.84 | CETP (0.37) | LPAR1LPAR5CETPMEN1ALDH1A1 | |
| SCHEMBL30289633 | 0.84 | CETP (0.37) | CETPMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL30289647 | 0.83 | CYP1A2 (0.40) | METCETPMEN1ALDH1A1KMT2A | |
| SCHEMBL30289703 | 0.80 | MEN1 (0.39) | CYP19A1MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL30289614 | 0.76 | ABL1 (0.59) | MST1RKDR | |
| SCHEMBL30367508 | 0.74 | LMNA (0.42) | MEN1ALDH1A1KMT2AHPGDRAB9A | |
| SCHEMBL30289651 | 0.65 | FYN (0.61) | MEN1ALDH1A1KMT2AKDM4EHPGD | |
| SCHEMBL23647531 | 0.64 | LTA4H (0.55) | LPAR1LPAR5MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894497-A | Imidazopyrimidine compounds, and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |