Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289922 | 0.81 | TAAR1 (0.52) | HPGDLMNASMN1; SMN2TUBB4ATUBB | |
| SCHEMBL30289868 | 0.77 | MAPT (0.52) | HPGDSMN1; SMN2TUBB4ATUBBTUBA3C | |
| SCHEMBL30289874 | 0.76 | MAPT (0.58) | HPGDSMN1; SMN2TUBB4ATUBBTUBA3C | |
| SCHEMBL30289893 | 0.74 | AKT1 (0.40) | SMN1; SMN2ALDH1A1GAAJAK2MAPK14 | |
| SCHEMBL9776737 | 0.72 | MAPT (0.60) | HPGDSMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL30289897 | 0.71 | KMT2A (0.75) | LMNASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL6670119 | 0.70 | TYMS (0.63) | HPGDLMNASMN1; SMN2TUBB4ATUBB | |
| SCHEMBL578054 | 0.70 | PARP14 (0.46) | HPGDLMNASMN1; SMN2TUBB4ATUBB | |
| SCHEMBL27321504 | 0.69 | MAPT (0.64) | HPGDSMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL3037555 | 0.69 | TUBB4A (0.56) | HPGDLMNASMN1; SMN2TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |