Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289899 | 0.84 | CXCR2 (0.41) | CXCR2LCKNAMPTEGFRKDR | |
| SCHEMBL30289911 | 0.81 | POLA1 (0.41) | LCKKDM4EALDH1A1SMN1; SMN2EGFR | |
| SCHEMBL30289906 | 0.75 | POLA1 (0.57) | LCKALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL30289853 | 0.75 | MAPT (0.48) | LCKKDM4EEGFR | |
| SCHEMBL30289796 | 0.74 | HPGD (0.43) | AKT1CXCR2JAK2KDM4EALDH1A1 | |
| SCHEMBL30289871 | 0.69 | KDM4E (0.49) | CXCR2LCKKDM4EALDH1A1EGFR | |
| SCHEMBL30289877 | 0.65 | XDH (0.49) | KDM4ENPC1ALDH1A1 | |
| SCHEMBL16306349 | 0.64 | PARP1 (0.60) | CDK4CCND1KDM4ESMN1; SMN2TYMS | |
| SCHEMBL30289841 | 0.63 | MAPT (0.40) | CXCR2LCKKDM4EALDH1A1GAA | |
| SCHEMBL19489880 | 0.63 | APP (0.52) | AKT1KDM4ENPC1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |