Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289960 | 0.86 | MAPT (0.47) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL30289989 | 0.83 | MEN1 (0.45) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL30289846 | 0.81 | KMT2A (0.62) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL4368274 | 0.77 | KDM4E (0.62) | MAPTKDM4ERAB9ASMN1; SMN2GAA | |
| SCHEMBL30289847 | 0.75 | MAPT (0.64) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL30289806 | 0.72 | MAPT (0.45) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL30289840 | 0.72 | MEN1 (0.53) | MAPTKMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL30289914 | 0.71 | PARP1 (0.56) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL30289904 | 0.70 | MAPT (0.52) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL30289793 | 0.70 | MAPT (0.55) | MAPTKMT2AMEN1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |