Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289858 | 0.86 | MAPT (0.49) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL30289960 | 0.86 | MAPT (0.47) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL30289840 | 0.80 | MEN1 (0.53) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL30289854 | 0.79 | KDM4E (0.71) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL30289811 | 0.78 | MAPT (0.40) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL30289904 | 0.78 | MAPT (0.52) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL30289989 | 0.78 | MEN1 (0.45) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL30289841 | 0.77 | MAPT (0.40) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL30289842 | 0.76 | KDM4E (0.47) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL30289911 | 0.74 | POLA1 (0.41) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |