Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289989 | 0.86 | MEN1 (0.45) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30289850 | 0.86 | MAPT (0.65) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30289806 | 0.86 | MAPT (0.45) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30289840 | 0.82 | MEN1 (0.53) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30289854 | 0.81 | KDM4E (0.71) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30289904 | 0.81 | MAPT (0.52) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30289842 | 0.79 | KDM4E (0.47) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30289867 | 0.77 | RIPK1 (0.49) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30289914 | 0.73 | PARP1 (0.56) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4368274 | 0.73 | KDM4E (0.62) | MAPTKDM4ESMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |