Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | C1R | P00736 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289847 | 0.86 | MAPT (0.64) | RIPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL30289838 | 0.86 | RIPK1 (0.49) | RIPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL32666084 | 0.85 | RIPK1 (0.67) | RIPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL30289904 | 0.80 | MAPT (0.52) | MEN1MAPTKMT2AKDM4EEGFR | |
| SCHEMBL30289854 | 0.78 | KDM4E (0.71) | MEN1MAPTKMT2AKDM4EPARP1 | |
| SCHEMBL30289842 | 0.78 | KDM4E (0.47) | MEN1MAPTKMT2AKDM4EF7 | |
| SCHEMBL30289960 | 0.77 | MAPT (0.47) | MEN1MAPTKMT2AKDM4EHDAC11 | |
| SCHEMBL32666092 | 0.77 | RIPK1 (0.73) | RIPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL32666091 | 0.77 | RIPK1 (0.73) | RIPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL7428429 | 0.76 | PARP1 (0.54) | MAPTKDM4EF7F3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |