Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | C1R | P00736 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289790 | 0.86 | MAPT (0.46) | KDM4EMEN1MAPTKMT2AHTT | |
| SCHEMBL30289904 | 0.82 | MAPT (0.52) | KDM4EMEN1MAPTKMT2APARP1 | |
| SCHEMBL30289854 | 0.80 | KDM4E (0.71) | KDM4EMEN1MAPTKMT2APARP1 | |
| SCHEMBL30289960 | 0.79 | MAPT (0.47) | KDM4EMEN1MAPTKMT2AHTT | |
| SCHEMBL30289867 | 0.78 | RIPK1 (0.49) | KDM4EMEN1MAPTKMT2APARP1 | |
| SCHEMBL30289806 | 0.76 | MAPT (0.45) | KDM4EMEN1MAPTKMT2AHTT | |
| SCHEMBL23066107 | 0.74 | PKM (0.64) | KDM4EMEN1MAPTKMT2AHTT | |
| SCHEMBL30289840 | 0.73 | MEN1 (0.53) | KDM4EMEN1MAPTKMT2AHTT | |
| SCHEMBL30289922 | 0.72 | TAAR1 (0.52) | KDM4EMEN1MAPTKMT2ARAB9A | |
| SCHEMBL30289841 | 0.71 | MAPT (0.40) | KDM4EMEN1MAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |