Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 10/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.49 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.49 |
| ▸ | DNMT3L | Q9UJW3 | 2/20 | 0.49 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.49 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24010134 | 1.00 | BRAF (0.49) | BRAFDNMT1EHMT1DNMT3LDNMT3A | |
| SCHEMBL24010281 | 0.88 | MAPK8 (0.52) | BRAFNT5EMAPTACVRL1 | |
| SCHEMBL30290887 | 0.88 | MAPK8 (0.52) | BRAFNT5EMAPTACVRL1 | |
| SCHEMBL30232750 | 0.84 | POLB (0.55) | DNMT1DNMT3LDNMT3ANT5EMEN1 | |
| SCHEMBL24006110 | 0.84 | POLB (0.55) | DNMT1DNMT3LDNMT3ANT5EMEN1 | |
| SCHEMBL30287677 | 0.84 | POLB (0.55) | DNMT1DNMT3LDNMT3ANT5EMEN1 | |
| SCHEMBL24003919 | 0.84 | POLB (0.55) | DNMT1DNMT3LDNMT3ANT5EMEN1 | |
| SCHEMBL25821615 | 0.83 | ACVRL1 (0.54) | BRAFMAPTACVRL1 | |
| SCHEMBL24010669 | 0.82 | KCNK3 (0.53) | DNMT1EHMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL30290811 | 0.82 | KCNK3 (0.53) | DNMT1EHMT1DNMT3LDNMT3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996721-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-04-21 | — | — | CN | disclosed |
| EP-4146212-A1 | AKT3 MODULATORS | Georgiamune LLC (US) | 2023-03-15 | — | — | EP | disclosed |