Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645470 | 1.00 | OPRM1 (0.38) | OPRM1OPRL1DPP4SIGMAR1HDAC4 | |
| SCHEMBL23645695 | 0.87 | HDAC4 (0.43) | OPRM1OPRL1DPP4SIGMAR1HDAC4 | |
| SCHEMBL30291457 | 0.78 | DPP4 (0.41) | OPRM1OPRL1DPP4SIGMAR1HDAC4 | |
| SCHEMBL23645516 | 0.78 | DPP4 (0.41) | OPRM1OPRL1DPP4SIGMAR1HDAC4 | |
| SCHEMBL23645672 | 0.77 | CTSL (0.41) | OPRM1OPRL1DPP4SIGMAR1HDAC4 | |
| SCHEMBL30291311 | 0.77 | CTSL (0.41) | OPRM1OPRL1DPP4SIGMAR1HDAC4 | |
| SCHEMBL23645517 | 0.70 | DPP4 (0.38) | OPRM1OPRL1DPP4SIGMAR1HDAC4 | |
| SCHEMBL30291293 | 0.70 | DPP4 (0.38) | OPRM1OPRL1DPP4SIGMAR1HDAC4 | |
| SCHEMBL22111662 | 0.70 | OPRM1 (0.48) | OPRM1OPRL1DPP4SIGMAR1EPHX2 | |
| SCHEMBL23380038 | 0.68 | DPP4 (0.49) | OPRM1OPRL1DPP4SIGMAR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113087700-B | Spirocyclic tetrahydroquinazolines | 苏州亚盛药业有限公司 | 2023-03-14 | — | — | CN | disclosed |