Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 6/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645672 | 1.00 | CTSL (0.41) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL23645512 | 0.86 | HDAC4 (0.40) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL23645516 | 0.78 | DPP4 (0.41) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL30291457 | 0.78 | DPP4 (0.41) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL23645470 | 0.77 | OPRM1 (0.38) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL30291397 | 0.77 | OPRM1 (0.38) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL8106440 | 0.72 | PDE7A (0.36) | OPRM1MEN1KMT2A | |
| SCHEMBL30291293 | 0.70 | DPP4 (0.38) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL23645517 | 0.70 | DPP4 (0.38) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL12173556 | 0.70 | PDE7A (0.37) | OPRM1MEN1KMT2AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113087700-B | Spirocyclic tetrahydroquinazolines | 苏州亚盛药业有限公司 | 2023-03-14 | — | — | CN | disclosed |