Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 11/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15666749 | 1.00 | CYP4F2 (0.42) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL22499253 | 0.81 | CYP4F2 (0.40) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL31179163 | 0.81 | RXRA (0.47) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL17258831 | 0.80 | RXRA (0.45) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL476884 | 0.80 | RXRA (0.42) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL17299830 | 0.79 | PDE9A (0.41) | — | |
| SCHEMBL29705484 | 0.79 | CYP4F2 (0.42) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL16793799 | 0.79 | CYP4F2 (0.42) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL17200351 | 0.79 | ALDH1A1 (0.43) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL24373169 | 0.79 | RXRA (0.42) | CYP4F2CYP4A11RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168392-A1 | SULFONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-26 | — | — | EP | disclosed |