SCHEMBL30292595

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)O)C(C)C

nearest known ligand 0.60

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	CTSB	P07858	1/20	0.56

▸	CTSD	P07339	3/20	0.53

▸	BACE1	P56817	10/20	0.53

▸	BACE2	Q9Y5Z0	1/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30292594	0.89	CTSB (0.53)	CTSBCTSDBACE1BACE2
SCHEMBL21192616	0.89	ACE (0.57)	CTSB
SCHEMBL21192611	0.89	ACE (0.57)	CTSB
SCHEMBL29427560	0.88	MME (0.58)	—
Gvnacsslf SCHEMBL29876091	0.87	BACE1 (0.55)	CTSDBACE1
SCHEMBL8060317	0.87	MME (0.59)	—
SCHEMBL8060325	0.87	MME (0.59)	—
SCHEMBL30617075	0.86	CTSB (0.59)	CTSBBACE1
SCHEMBL29966332	0.86	REN (0.57)	—
SCHEMBL29896984	0.86	MME (0.52)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20250152656-A1	INHIBITION OF TREM RECEPTOR SIGNALING WITH PEPTIDE VARIANTS	SIGNABLOK INC (US)	2025-05-15	—	—	US	disclosed
US-12168034-B2	Inhibition of TREM receptor signaling with peptide variants	SIGNABLOK, INC. (US)	2024-12-17	—	—	US	disclosed
US-20230364179-A1	INHIBITION OF TREM RECEPTOR SIGNALING WITH PEPTIDE VARIANTS	SIGNABLOK INC.	2023-11-16	—	—	US	disclosed
US-11638739-B2	Inhibition of TREM receptor signaling with peptide variants	SIGNABLOK, INC. (US)	2023-05-02	—	—	US	disclosed