Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 15/20 | 0.55 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29677701 | 0.88 | BACE1 (0.56) | BACE1CTSD | |
| SCHEMBL30292595 | 0.87 | CTSB (0.56) | BACE1CTSD | |
| SCHEMBL30437795 | 0.87 | OPRM1 (0.55) | BACE1CTSD | |
| SCHEMBL31461916 | 0.83 | TFPI (0.61) | BACE1CTSD | |
| SCHEMBL15669773 | 0.83 | TFPI (0.53) | BACE1 | |
| SCHEMBL30512530 | 0.82 | BACE1 (0.57) | BACE1CTSD | |
| SCHEMBL29611334 | 0.82 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL21192616 | 0.81 | ACE (0.57) | — | |
| SCHEMBL21192611 | 0.81 | ACE (0.57) | — | |
| SCHEMBL30080577 | 0.81 | GRIN2D (0.42) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12116424-B2 | Compounds and compositions for modulating Listeria virulence | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2024-10-15 | — | — | US | disclosed |
| US-20220298208-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LISTERIA VIRULENCE | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2022-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220298208-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LISTERIA VIRULENCE | LTN1, LOXL1, LTA | BACE1 1211/4885CTSD 3429/4885 |
| US-12116424-B2 | Compounds and compositions for modulating Listeria virulence | LTN1, LOXL1, LTA | BACE1 1211/4885CTSD 3429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.