Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | AXL | P30530 | 1/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | APAF1 | O14727 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4377723 | 0.87 | CA2 (0.53) | KDM4EGAAALDH1A1POLBPDGFRB | |
| SCHEMBL9269640 | 0.81 | AXL (0.64) | KDM4EGAAALDH1A1POLBAXL | |
| SCHEMBL1289714 | 0.80 | KDM4E (0.57) | KDM4EGAAALDH1A1POLBAXL | |
| SCHEMBL9296104 | 0.79 | AXL (0.65) | KDM4EGAAALDH1A1POLBAXL | |
| SCHEMBL2731348 | 0.78 | KDM4E (0.58) | KDM4EGAAALDH1A1POLBAXL | |
| SCHEMBL830643 | 0.78 | KDM4E (0.58) | KDM4EGAAALDH1A1POLBAXL | |
| SCHEMBL4397800 | 0.76 | KDM4E (0.57) | KDM4EGAAALDH1A1POLBAXL | |
| SCHEMBL9293307 | 0.76 | KDM4E (0.65) | KDM4EGAAALDH1A1POLBMAPT | |
| SCHEMBL31222308 | 0.76 | KDM4E (1.00) | KDM4EGAAALDH1A1POLBAXL | |
| SCHEMBL9293461 | 0.76 | KDM4E (0.65) | KDM4EGAAALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988093-B | Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine | 广东东阳光药业有限公司 | 2023-04-07 | — | — | CN | disclosed |