SCHEMBL30293261

SCHEMBL30293261

CCOc1ccc2[nH]c(=O)c3ccccc3c2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.62
MAPT P10636 2/20 0.62
ESR2 Q92731 1/20 0.62
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
KDM4E B2RXH2 4/20 0.58
ALDH1A1 P00352 4/20 0.58
TSHR P16473 1/20 0.58
PARP1 P09874 6/20 0.54
PARP15 Q460N3 2/20 0.53
TNKS2 Q9H2K2 2/20 0.53
PARP10 Q53GL7 1/20 0.53
RXFP1 Q9HBX9 1/20 0.52
GABRP O00591 1/20 0.52
GABRD O14764 1/20 0.52
GABRA1 P14867 1/20 0.52
GABRB1 P18505 1/20 0.52
GABRG2 P18507 1/20 0.52
GABRB3 P28472 1/20 0.52
GABRA5 P31644 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14486713 1.00 HSD17B10 (0.62) HSD17B10MAPTESR2MEN1KMT2A
SCHEMBL15466453 0.84 ALDH1A1 (0.67) HSD17B10MAPTESR2MEN1KMT2A
SCHEMBL19583371 0.82 HSD17B10 (0.65) HSD17B10MAPTESR2MEN1KMT2A
SCHEMBL7032301 0.81 HSD17B10 (0.61) HSD17B10MAPTESR2MEN1KMT2A
SCHEMBL21676421 0.77 HSD17B10 (1.00) HSD17B10MAPTESR2MEN1KMT2A
SCHEMBL4486207 0.76 CTSV (0.70) HSD17B10MAPTESR2MEN1KMT2A
Ether SCHEMBL11582783 0.76 PARP1 (0.71) HSD17B10MAPTMEN1KMT2AKDM4E
SCHEMBL5336901 0.75 ALDH1A1 (0.68) HSD17B10MAPTESR2MEN1KMT2A
SCHEMBL19242935 0.75 KDM4E (0.66) HSD17B10MAPTESR2MEN1KMT2A
SCHEMBL16938460 0.74 KDM4E (0.78) HSD17B10MAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109988093-B Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine 广东东阳光药业有限公司 2023-04-07 CN disclosed