SCHEMBL30293834

SCHEMBL30293834

CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NTSR2 O95665 4/20 0.45
▸ NTSR1 P30989 4/20 0.45
▸ BACE1 P56817 3/20 0.42
▸ SORT1 Q99523 3/20 0.41
▸ MAGI3 Q5TCQ9 1/20 0.40
▸ MDM4 O15151 1/20 0.39
▸ MDM2 Q00987 1/20 0.39
▸ CCNA2 P20248 2/20 0.39
▸ CDK2 P24941 2/20 0.39
▸ CCNA1 P78396 2/20 0.39
▸ F2 P00734 2/20 0.39
▸ SLC15A2 Q16348 1/20 0.39
▸ C5AR1 P21730 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30338373 0.94 BACE1 (0.46) NTSR2NTSR1BACE1MAGI3
SCHEMBL31180771 0.92 NTSR2 (0.46) NTSR2NTSR1BACE1SORT1CCNA2
SCHEMBL30368368 0.89 GLP1R (0.42) BACE1MDM4MDM2C5AR1
SCHEMBL31256965 0.89 BACE1 (0.48) BACE1CCNA2CDK2CCNA1
SCHEMBL30433504 0.86 NTSR2 (0.48) NTSR2NTSR1BACE1SORT1MDM4
SCHEMBL31574018 0.86 BACE1 (0.44) BACE1
SCHEMBL10619527 0.86 BACE1 (0.48) BACE1CCNA2CDK2CCNA1
SCHEMBL10619539 0.86 BACE1 (0.48) BACE1CCNA2CDK2CCNA1
SCHEMBL29435292 0.85 BACE1 (0.51) BACE1F2
SCHEMBL29732685 0.85 SLC15A2 (0.44) NTSR2NTSR1SLC15A2C5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118159552-A Novel peptides as potent and selective GIP receptor agonists 赛诺菲 2024-06-07 — — CN disclosed
US-20230103631-A1 PEPTIDES AS SELECTIVE GIP RECEPTOR AGONISTS SANOFI (FR) 2023-04-06 — — US disclosed
CN-115884982-A Peptides as selective GIP receptor agonists 赛诺菲 2023-03-31 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230103631-A1 PEPTIDES AS SELECTIVE GIP RECEPTOR AGONISTS GIPR, GLP1R, GPR119 NTSR2 30/4885NTSR1 24/4885BACE1 3319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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