SCHEMBL30368368

CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	5/20	0.42

▸	NPY4R	P50391	6/20	0.41

▸	NPY1R	P25929	5/20	0.41

▸	NPY2R	P49146	4/20	0.41

▸	NPY5R	Q15761	4/20	0.41

▸	MDM4	O15151	1/20	0.40

▸	MDM2	Q00987	1/20	0.40

▸	BACE1	P56817	1/20	0.40

▸	VIPR2	P41587	4/20	0.40

▸	VIPR1	P32241	2/20	0.40

▸	C5AR1	P21730	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30369010	0.94	GLP1R (0.45)	GLP1RBACE1VIPR2VIPR1
SCHEMBL30445562	0.90	APLNR (0.43)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL31366748	0.90	GLP1R (0.51)	GLP1RVIPR2VIPR1
SCHEMBL30293834	0.89	NTSR2 (0.45)	MDM4MDM2BACE1C5AR1
SCHEMBL31256985	0.89	GLP1R (0.45)	GLP1RBACE1VIPR2VIPR1
SCHEMBL30887565	0.88	KISS1R (0.51)	GLP1RBACE1VIPR2VIPR1
SCHEMBL31353031	0.88	GLP1R (0.51)	GLP1RVIPR1
SCHEMBL30952096	0.88	NPY4R (0.43)	GLP1RNPY4RNPY1RNPY2RNPY5R
SCHEMBL30293824	0.87	GLP1R (0.40)	GLP1RNPY4RNPY1RNPY2RNPY5R
SCHEMBL29541058	0.87	VIPR2 (0.47)	GLP1RVIPR2VIPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-115884982-A	Peptides as selective GIP receptor agonists	赛诺菲	2023-03-31	—	—	CN	claimed