SCHEMBL6902991

SCHEMBL6902991

Cc1ccc2c(c1)CCCC2C

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 2/20 0.42
LMNA P02545 1/20 0.38
SLC6A4 P31645 2/20 0.37
ACHE P22303 1/20 0.37
HTR2C P28335 2/20 0.37
HTR2A P28223 1/20 0.37
HTR2B P41595 1/20 0.37
ALDH1A1 P00352 1/20 0.37
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A3 Q01959 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
HRH2 P25021 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL413401 0.88 SRD5A1 (0.47) SRD5A1SLC6A4ACHEHTR2CHTR2A
SCHEMBL30298331 0.88 SRD5A1 (0.47) SRD5A1SLC6A4ACHEHTR2CHTR2A
SCHEMBL8900410 0.85 ACHE (0.41) LMNASLC6A4ACHEHTR2CHTR2A
SCHEMBL12410189 0.79 UGT2B17 (0.51) SRD5A1LMNAMEN1KMT2AESR1
SCHEMBL10069514 0.79 ACHE (0.41) SRD5A1LMNASLC6A4ACHEALDH1A1
SCHEMBL12352398 0.79 ACHE (0.41) SRD5A1LMNASLC6A4ACHEALDH1A1
SCHEMBL12352440 0.79 ACHE (0.41) SRD5A1LMNASLC6A4ACHEALDH1A1
SCHEMBL21870100 0.79 UGT2B17 (0.51) SRD5A1LMNAMEN1KMT2AESR1
SCHEMBL23315623 0.79 HTR2C (0.36) HTR2CHTR2AHTR2BESR1ESR2
SCHEMBL16257828 0.79 SRD5A1 (0.43) SRD5A1HTR2CHTR2AHTR2BESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220152587-A1 JUTE STEM-SUPPORTED PALLADIUM-NPS AND USE AS DIP-CATALYSTS FOR AQUEOUS TRANSFER HYDROGENATION KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2022-05-19 US claimed
EP-0582108-B1 Process for production of dimethyltetralin MITSUBISHI GAS CHEMICAL CO (JP) 1996-10-09 EP claimed
US-5396007-A Dehydrogenating dimethyltetrahydronaphthalene in diluted medium using palladium or platinum catalyst supported by activated carbon MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-03-07 US claimed
US-5396008-A Cyclization MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1995-03-07 US claimed
EP-0582108-A1 Process for production of dimethyltetralin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1994-02-09 EP claimed
US-5189234-A Dimethyltetralin to dimethylnaphthalene AMOCO CORPORATION (US) 1993-02-23 US claimed
US-11446636-B2 Jute stem-supported palladium-NPS and use as dip-catalysts for aqueous transfer hydrogenation KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2022-09-20 US disclosed
US-20220152587-A1 JUTE STEM-SUPPORTED PALLADIUM-NPS AND USE AS DIP-CATALYSTS FOR AQUEOUS TRANSFER HYDROGENATION KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2022-05-19 US disclosed
EP-3103789-B1 METHOD FOR PRODUCING (R)-1,1,3-TRIMETHYL-4-AMINOINDANE SUMITOMO CHEMICAL CO (JP) 2018-10-31 EP disclosed
EP-2915801-B1 PRODUCTION METHOD FOR RACEMATE OF COMPOUND SUMITOMO CHEMICAL CO (JP) 2018-07-04 EP disclosed
US-9765032-B2 Method for producing (R)-1,1,3-trimethyl-4-aminoindane SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-19 US disclosed
US-20170166532-A1 METHOD FOR PRODUCING (R)-1,1,3-TRIMETHYL-4-AMINOINDANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-15 US disclosed
EP-3103789-A1 METHOD FOR PRODUCING (R)-1,1,3-TRIMETHYL-4-AMINOINDANE Sumitomo Chemical Company Limited (JP) 2016-12-14 EP disclosed
EP-0687248-B1 CRYSTALLIZATION OF 2,6-DIMETHYLNAPHTHALENE AMOCO CORP (US) 1999-10-20 EP disclosed
EP-0926114-A2 Crystallization of 2,6-Dimethylnaphthalene AMOCO CORPORATION (US) 1999-06-30 EP disclosed
US-5510563-A ALKENYLATION, CYCLIZATION, DEHYDROGENATION, AND ISOMERIZATION AMOCO CORPORATION (US) 1996-04-23 US disclosed
US-5365001-A Catalytic cyclization of alkenebenzene in the presence of hydrogen TEIJIN LIMITED (JP) 1994-11-15 US disclosed
EP-0594856-A1 PROCESS FOR PRODUCING DIALKYLNAPHTHALENE TEIJIN LIMITED (JP) 1994-05-04 EP disclosed
US-4382851-A HYDROGEN SULFIDE, CARBON MONOXIDE, AROMATIC HYDROCARBONS MOBIL OIL CORPORATION (US) 1983-05-10 US disclosed
US-3997616-A FROM ALKENYLBENZENE, CYCLIZATION CATALYST TEIJIN LIMITED (JA) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170166532-A1 METHOD FOR PRODUCING (R)-1,1,3-TRIMETHYL-4-AMINOINDANE HTR1D, TPH1, HTR1A SRD5A1 67/4885LMNA 2501/4885SLC6A4 1189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.