⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL3439691 | 0.86 | — | — | |
| Leucine SCHEMBL12757165 | 0.86 | — | — | |
| Leucine SCHEMBL8568063 | 0.82 | SLC7A5 (1.00) | — | |
| Leucine SCHEMBL20362356 | 0.82 | — | — | |
| Leucine SCHEMBL331557 | 0.82 | SLC7A5 (1.00) | — | |
| Leucine SCHEMBL25241602 | 0.82 | SLC7A5 (1.00) | — | |
| Leucine SCHEMBL2478164 | 0.82 | SLC7A5 (1.00) | — | |
| Leucine SCHEMBL8568060 | 0.82 | SLC7A5 (1.00) | — | |
| Leucine SCHEMBL175940 | 0.82 | SLC7A5 (1.00) | — | |
| D-Leucine SCHEMBL9100148 | 0.82 | SLC7A5 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4569090-A2 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | Trailhead Biosystems Inc. (US) | 2025-06-18 | — | — | EP | claimed |
| CN-119654404-A | Methods and compositions for producing oligodendrocyte progenitor cells | 特雷尔赫德生物系统股份有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-118591620-A | Methods and compositions for generating and maturing human forebrain neural progenitor cells into small albumin positive interneurons | 特雷尔赫德生物系统股份有限公司 | 2024-09-03 | — | — | CN | claimed |
| WO-2024063818-A9 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2024-05-23 | — | — | WO | claimed |
| WO-2024063818-A2 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2024-03-28 | — | — | WO | claimed |
| US-20240043798-A1 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. | 2024-02-08 | — | — | US | claimed |
| US-20230332103-A1 | Methods and Compositions for Generating Human Forebrain Neural Progenitor Cells and for Maturation Thereof to Parvalbumin+ Interneurons | TRAILHEAD BIOSYSTEMS INC. | 2023-10-19 | — | — | US | claimed |
| US-20250304916-A1 | METHODS AND COMPOSITIONS FOR GENERATING VASCULAR LEPTOMENINGEAL CELLS | TRAILHEAD BIOSYSTEMS INC (US) | 2025-10-02 | — | — | US | disclosed |
| EP-4569090-A2 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | Trailhead Biosystems Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119654404-A | Methods and compositions for producing oligodendrocyte progenitor cells | 特雷尔赫德生物系统股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| EP-4423252-A1 | METHODS AND COMPOSITIONS FOR GENERATING HUMAN FOREBRAIN NEURAL PROGENITOR CELLS AND FOR MATURATION THEREOF TO PARVALBUMIN+ INTERNEURONS | Trailhead Biosystems Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-118591620-A | Methods and compositions for generating and maturing human forebrain neural progenitor cells into small albumin positive interneurons | 特雷尔赫德生物系统股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| WO-2024063818-A9 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024063818-A2 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| US-20240043798-A1 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. | 2024-02-08 | — | — | US | disclosed |
| US-20230332103-A1 | Methods and Compositions for Generating Human Forebrain Neural Progenitor Cells and for Maturation Thereof to Parvalbumin+ Interneurons | TRAILHEAD BIOSYSTEMS INC. | 2023-10-19 | — | — | US | disclosed |
| WO-2023075913-A1 | METHODS AND COMPOSITIONS FOR GENERATING HUMAN FOREBRAIN NEURAL PROGENITOR CELLS AND FOR MATURATION THEREOF TO PARVALBUMIN+ INTERNEURONS | TRAILHEAD BIOSYSTEMS INC. (US) | 2023-05-04 | — | — | WO | disclosed |