Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.69 |
| ▸ | DRD1 | P21728 | 1/20 | 0.69 |
| ▸ | HTR1A | P08908 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CCR3 | P51677 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27008246 | 1.00 | DRD2 (0.69) | DRD2DRD1HTR1APOLBCCR3 | |
| SCHEMBL30389686 | 0.88 | HTR1A (0.65) | DRD2DRD1HTR1ADRD3MAPT | |
| SCHEMBL24076569 | 0.88 | HTR1A (0.65) | DRD2DRD1HTR1ADRD3MAPT | |
| SCHEMBL30301412 | 0.85 | DRD2 (0.66) | DRD2DRD1HTR1APOLBDRD3 | |
| SCHEMBL24076498 | 0.85 | DRD2 (0.66) | DRD2DRD1HTR1APOLBDRD3 | |
| SCHEMBL6396896 | 0.84 | KMT2A (0.65) | HTR1APOLBCCR3MAPT | |
| SCHEMBL27014520 | 0.82 | CCR3 (0.82) | HTR1APOLBCCR3DRD4MAPT | |
| SCHEMBL30389381 | 0.82 | CCR3 (0.82) | HTR1APOLBCCR3DRD4MAPT | |
| SCHEMBL30301391 | 0.82 | DRD2 (0.74) | DRD2HTR1ADRD3DRD4SLC6A4 | |
| SCHEMBL27014523 | 0.82 | DRD2 (0.74) | DRD2HTR1ADRD3DRD4SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057049-A | Carboxamide derivatives and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-02 | — | — | CN | claimed |
| CN-116057049-A | Carboxamide derivatives and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-02 | — | — | CN | disclosed |
| EP-4159725-A1 | CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2023-04-05 | — | — | EP | disclosed |