Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.66 |
| ▸ | DRD3 | P35462 | 7/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24076498 | 1.00 | DRD2 (0.66) | DRD2DRD3ADRA1APOLBDRD4 | |
| SCHEMBL30301397 | 0.85 | DRD2 (0.69) | DRD2DRD3POLBDRD4DRD1 | |
| SCHEMBL27008246 | 0.85 | DRD2 (0.69) | DRD2DRD3POLBDRD4DRD1 | |
| SCHEMBL30389513 | 0.83 | DRD3 (0.74) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL27014500 | 0.83 | DRD3 (0.74) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL11439568 | 0.81 | DRD3 (0.65) | DRD2DRD3ADRA1APOLBHTR1A | |
| SCHEMBL11286122 | 0.81 | DRD3 (0.56) | DRD2DRD3ADRA1APOLBHTR1A | |
| Fluprazine SCHEMBL2110425 | 0.81 | DRD2 (0.62) | DRD2DRD3ADRA1APOLBHTR1A | |
| Fluprazine SCHEMBL29445768 | 0.81 | DRD2 (0.62) | DRD2DRD3ADRA1APOLBHTR1A | |
| SCHEMBL8272365 | 0.81 | ALDH1A1 (0.63) | DRD2DRD3ADRA1APOLBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057049-A | Carboxamide derivatives and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-02 | — | — | CN | claimed |
| CN-116057049-A | Carboxamide derivatives and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-02 | — | — | CN | disclosed |
| EP-4159725-A1 | CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2023-04-05 | — | — | EP | disclosed |