Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30301453 | 0.79 | PRKACA (0.44) | ALDH1A1NPSR1TSHRPRKACAPRKACG | |
| SCHEMBL23160276 | 0.79 | TSHR (0.46) | ALDH1A1NPSR1TDP1TSHRPSEN1 | |
| SCHEMBL29731691 | 0.79 | TSHR (0.46) | ALDH1A1NPSR1TDP1TSHRPSEN1 | |
| SCHEMBL30301483 | 0.72 | GAA (0.38) | ALDH1A1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL20472046 | 0.71 | ALDH1A1 (0.52) | ALDH1A1NPSR1TDP1TSHRUSP2 | |
| SCHEMBL29863299 | 0.69 | POLB (0.41) | ALDH1A1NPSR1TDP1TSHRPRKACA | |
| SCHEMBL22413013 | 0.69 | POLB (0.41) | ALDH1A1NPSR1TDP1TSHRPRKACA | |
| SCHEMBL16532656 | 0.69 | KDM4E (0.53) | ALDH1A1NPSR1TUBB4ATUBBTUBA3C | |
| SCHEMBL18179687 | 0.68 | ACR (0.51) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL24610141 | 0.65 | ALDH1A1 (0.43) | ALDH1A1NPSR1TDP1TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023025109-A1 | TOLL-LIKE RECEPTOR INHIBITOR AND PREPARATION AND APPLICATION THEREOF | 上海维申医药有限公司 | 2023-03-02 | — | — | WO | disclosed |