SCHEMBL30301548

SCHEMBL30301548

Nc1ccc(Nc2cccc3c2C(=O)c2cccc(Nc4ccc(N)cc4)c2C3=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNG2 P59768 3/20 0.52
GNB1 P62873 3/20 0.52
MAPT P10636 4/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
ALOX15 P16050 2/20 0.52
HSD17B10 Q99714 2/20 0.52
KDM4E B2RXH2 1/20 0.52
TP53 P04637 1/20 0.52
APP P05067 1/20 0.52
HPGD P15428 1/20 0.52
SNCA P37840 1/20 0.52
BLM P54132 1/20 0.52
MET P08581 3/20 0.48
L3MBTL1 Q9Y468 3/20 0.47
MAPK1 P28482 3/20 0.47
RAB9A P51151 2/20 0.47
EGFR P00533 1/20 0.47
PABPC1 P11940 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ALDH1A1 P00352 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7061696 1.00 GNG2 (0.52) GNG2GNB1MAPTSMN1; SMN2ALOX15
SCHEMBL7064424 0.95 MAPK1 (0.56) GNG2GNB1MAPTSMN1; SMN2ALOX15
SCHEMBL30608528 0.95 MAPT (0.50) GNG2GNB1MAPTSMN1; SMN2ALOX15
SCHEMBL11879902 0.86 GNG2 (0.43) GNG2GNB1MAPTSMN1; SMN2ALOX15
SCHEMBL11872441 0.86 GNG2 (0.63) GNG2GNB1MAPTSMN1; SMN2ALOX15
SCHEMBL2612577 0.83 MAPT (0.56) GNG2GNB1MAPTSMN1; SMN2ALOX15
SCHEMBL11810473 0.83 MAOA (0.54) GNG2GNB1MAPTSMN1; SMN2ALOX15
SCHEMBL9308589 0.82 MAPK1 (0.50) GNG2GNB1MAPTSMN1; SMN2KDM4E
SCHEMBL7152111 0.82 RAB9A (0.56) GNG2GNB1MAPTSMN1; SMN2KDM4E
SCHEMBL11602772 0.82 DHODH (0.49) GNG2GNB1MAPTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115821417-B Preparation method of copolymerized self-colored aramid fiber and copolymerized self-colored aramid fiber 中国石油化工股份有限公司 2024-12-03 CN disclosed
CN-115821417-A Preparation method of copolymerized self-coloring aramid fiber and copolymerized self-coloring aramid fiber 中国石油化工股份有限公司 2023-03-21 CN disclosed