Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29995067 | 0.87 | DNM1 (0.43) | ALDH1A1KMT2ASMN1; SMN2P2RX4MEN1 | |
| SCHEMBL7415595 | 0.84 | PLK1 (0.43) | ALDH1A1KMT2ASMN1; SMN2MEN1MET | |
| SCHEMBL20100768 | 0.79 | RPA1 (0.43) | ALDH1A1KMT2ASMN1; SMN2MEN1PARP1 | |
| SCHEMBL30961044 | 0.72 | NPC1 (0.39) | ALDH1A1KMT2AMEN1PARP1NPC1 | |
| SCHEMBL15083751 | 0.71 | PARP1 (0.47) | ALDH1A1KMT2ASMN1; SMN2MEN1PARP1 | |
| SCHEMBL29994664 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1PARP1TNKS | |
| SCHEMBL31189203 | 0.70 | P2RX4 (0.68) | ALDH1A1KMT2ASMN1; SMN2P2RX4MEN1 | |
| SCHEMBL8348004 | 0.70 | P2RX4 (0.68) | ALDH1A1KMT2ASMN1; SMN2P2RX4MEN1 | |
| SCHEMBL17297888 | 0.68 | PARP1 (0.41) | ALDH1A1KMT2AMEN1PARP1 | |
| SCHEMBL9917406 | 0.67 | P2RX4 (0.59) | KMT2ASMN1; SMN2P2RX4MEN1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197225-B | Five-membered heterocyclic quinazolinone compound and preparation method thereof | 贵州大学 | 2023-04-11 | — | — | CN | disclosed |