Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30306362 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APARP1MAPT | |
| SCHEMBL20100768 | 0.79 | RPA1 (0.43) | PLK1ALDH1A1MEN1KMT2APARP1 | |
| SCHEMBL29995067 | 0.71 | DNM1 (0.43) | ALDH1A1MEN1KMT2AMAPTTP53 | |
| SCHEMBL15083751 | 0.71 | PARP1 (0.47) | ALDH1A1MEN1KMT2APARP1LCK | |
| SCHEMBL29994664 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2APARP1MAPT | |
| SCHEMBL30961044 | 0.70 | NPC1 (0.39) | PLK1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL17297888 | 0.68 | PARP1 (0.41) | PLK1ALDH1A1MEN1KMT2APARP1 | |
| SCHEMBL6858242 | 0.65 | HPGD (0.41) | ALDH1A1MEN1TSHRKMT2APARP1 | |
| SCHEMBL5214046 | 0.64 | LOXL2 (0.57) | ALDH1A1MEN1KMT2APARP1MAOB | |
| SCHEMBL15180301 | 0.64 | RPA1 (0.57) | ALDH1A1MEN1KMT2APARP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002543199-A | — | — | 2002-12-17 | — | — | JP | claimed |
| EP-1177195-A1 | 1-AMINO TRIAZOLO 4,3-a! QUINAZOLINE-5-ONES AND OR -5-THIONES INHIBITING PHOSPHODIESTERASE IV | WARNER-LAMBERT COMPANY (US) | 2002-02-06 | — | — | EP | claimed |
| WO-2000066584-A1 | 1-AMINO TRIAZOLO¢4,3-a! QUINAZOLINE-5-ONES AND OR -5-THIONES INHIBITING PHOSPHODIESTERASE IV | WARNER-LAMBERT COMPANY (US) | 2000-11-09 | — | — | WO | claimed |