SCHEMBL30306372

SCHEMBL30306372

CCCN(C)c1nc2c(N)nc3ccccc3c2n1CC(C)(C)O

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.66
TLR8 Q9NR97 7/20 0.66
NUDT1 P36639 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL147627 1.00 TLR7 (0.66) TLR7TLR8NUDT1
SCHEMBL12213294 0.91 TLR7 (0.60) TLR7TLR8NUDT1
SCHEMBL10264358 0.88 TLR7 (0.51) TLR7TLR8NUDT1
SCHEMBL10264278 0.88 TLR7 (0.51) TLR7TLR8NUDT1
SCHEMBL3265607 0.87 TLR7 (0.63) TLR7TLR8NUDT1
SCHEMBL10264662 0.87 TLR7 (0.50) TLR7TLR8NUDT1
SCHEMBL3179251 0.87 TLR7 (0.49) TLR7TLR8NUDT1
SCHEMBL10265062 0.85 TLR7 (0.48) TLR7TLR8NUDT1
SCHEMBL13505053 0.84 TLR7 (0.62) TLR7TLR8NUDT1
SCHEMBL144931 0.83 TLR7 (0.53) TLR7TLR8NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4183412-B1 RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-08-14 EP disclosed
US-20230348574-A1 RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-11-02 US disclosed
US-20230072995-A1 RSV IMMUNIZATION REGIMEN GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348574-A1 RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME RNASEL, TIMCC, RNGTT TLR7 349/4885TLR8 1489/4885NUDT1 1255/4885
US-20230072995-A1 RSV IMMUNIZATION REGIMEN IL5, IL15, IFNG TLR7 48/4885TLR8 77/4885NUDT1 3283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.