Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 2/20 | 0.42 |
| ▸ | PRKCB | P05771 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.42 |
| ▸ | CDK9 | P50750 | 2/20 | 0.42 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.42 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.42 |
| ▸ | STK16 | O75716 | 1/20 | 0.42 |
| ▸ | PAK3 | O75914 | 1/20 | 0.42 |
| ▸ | CDK14 | O94921 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524369 | 0.74 | PRKCG (0.69) | PRKCGPRKCBPRKCAPRKCECDK9 | |
| SCHEMBL6438378 | 0.72 | L3MBTL1 (0.47) | TLR9TLR8TLR7CDK9L3MBTL1 | |
| SCHEMBL3150985 | 0.63 | KDM4E (0.65) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL29992091 | 0.63 | CYP1A2 (0.71) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1DDB1 | |
| SCHEMBL20804356 | 0.63 | CYP1A2 (0.71) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1DDB1 | |
| SCHEMBL1333260 | 0.63 | CYP1A2 (0.71) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1DDB1 | |
| SCHEMBL1331974 | 0.63 | CYP1A2 (0.71) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1DDB1 | |
| SCHEMBL30141847 | 0.63 | CYP1A2 (0.71) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1DDB1 | |
| SCHEMBL13456363 | 0.63 | L3MBTL1 (0.62) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL2495181 | 0.63 | L3MBTL1 (0.62) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4171637-A1 | THERAPEUTIC TREATMENT USING PROTEIN KINASE C (PKC) INHIBITORS AND CYTOTOXIC AGENTS | Cambridge Enterprise Limited (GB) | 2023-05-03 | — | — | EP | disclosed |