Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5251920 | 0.80 | TUBB4A (0.54) | NPC1KDM4EALDH1A1RAB9AKMT2A | |
| SCHEMBL588318 | 0.72 | PRKCG (0.55) | L3MBTL1CDK9NPC1KDM4EPOLB | |
| SCHEMBL30306703 | 0.72 | TLR9 (0.42) | L3MBTL1CCNT1CDK9KDM4EPOLB | |
| SCHEMBL28451423 | 0.67 | L3MBTL1 (0.63) | L3MBTL1NPC1KDM4EPOLBCYP2D6 | |
| SCHEMBL21061928 | 0.67 | L3MBTL1 (0.63) | L3MBTL1NPC1KDM4EPOLBCYP2D6 | |
| SCHEMBL30435016 | 0.67 | L3MBTL1 (0.63) | L3MBTL1NPC1KDM4EPOLBCYP2D6 | |
| SCHEMBL28451514 | 0.67 | L3MBTL1 (0.63) | L3MBTL1NPC1KDM4EPOLBCYP2D6 | |
| SCHEMBL28663269 | 0.67 | L3MBTL1 (0.62) | L3MBTL1NPC1KDM4EPOLBCYP2D6 | |
| SCHEMBL20097550 | 0.66 | ALDH1A1 (0.73) | L3MBTL1KDM4EPOLBCYP2D6CYP2C19 | |
| SCHEMBL6994948 | 0.66 | L3MBTL1 (0.97) | L3MBTL1KDM4EPOLBCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523313-A1 | CRYSTALLINE 2,5-DIONE-3-(1-METHYL-1H-INDOL-3-YL)-4- 1-(PYRIDIN-2-YLMETHYL)PIPERIDIN-4-YL]-1H-INDOL-3-YL]-1H-PYRROLE MONO-HYDROCHLORIDE | ELI LILLY AND COMPANY (US) | 2005-04-20 | — | — | EP | disclosed |
| WO-2004006928-A1 | CRYSTALLINE 2,5-DIONE-3-(1-METHYL-1H-INDOL-3-YL)-4-[1-(PYRIDIN-2-YLMETHYL)PIPERIDIN-4-YL]-1H-INDOL-3-YL]-1H-PYRROLE MONO-HYDROCHLORIDE | ELI LILLY AND COMPANY (US) | 2004-01-22 | — | — | WO | disclosed |