Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227372 | 0.85 | TP53 (0.39) | NTRK1NTRK2HDAC4HDAC2HDAC8 | |
| SCHEMBL30554743 | 0.85 | TP53 (0.39) | NTRK1NTRK2HDAC4HDAC2HDAC8 | |
| SCHEMBL28078075 | 0.84 | ALOX5 (0.43) | NTRK1NTRK2HDAC4HDAC2HDAC8 | |
| SCHEMBL25277498 | 0.84 | ALDH1A1 (0.43) | NTRK1NTRK2MEN1KMT2AALDH1A1 | |
| Methoxymethane SCHEMBL27988234 | 0.83 | ALOX5 (0.42) | NTRK1NTRK2HDAC4HDAC2HDAC8 | |
| SCHEMBL28243397 | 0.82 | CYP1A2 (0.50) | MEN1KMT2AALDH1A1TDP1CYP1A2 | |
| SCHEMBL29227267 | 0.81 | CYP1A2 (0.37) | NTRK1NTRK2MEN1KMT2AALDH1A1 | |
| SCHEMBL25233982 | 0.79 | CYP1A2 (0.53) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL29419845 | 0.79 | ADORA3 (0.46) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL29227271 | 0.79 | ABCG2 (0.39) | NTRK1NTRK2HDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149307-B | Bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2023-04-11 | — | — | CN | disclosed |