Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 6/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | ATM | Q13315 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | MITF | O75030 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16211002 | 1.00 | TNFRSF1A (0.78) | TNFRSF1AMAPTLMNAHTTATM | |
| SCHEMBL16211003 | 1.00 | TNFRSF1A (0.78) | TNFRSF1AMAPTLMNAHTTATM | |
| SCHEMBL1799936 | 0.92 | TNFRSF1A (0.78) | TNFRSF1AMAPTLMNAHTTATM | |
| SCHEMBL1799934 | 0.92 | TNFRSF1A (0.78) | TNFRSF1AMAPTLMNAHTTATM | |
| SCHEMBL1797256 | 0.88 | MAPT (0.73) | TNFRSF1AMAPTLMNAHTTATM | |
| SCHEMBL1797257 | 0.88 | MAPT (0.73) | TNFRSF1AMAPTLMNAHTTATM | |
| SCHEMBL19468567 | 0.84 | ABCG2 (0.86) | TNFRSF1AMAPTLMNAATMSMN1; SMN2 | |
| SCHEMBL16181498 | 0.84 | ABCG2 (0.67) | TNFRSF1AMAPTLMNAATMMEN1 | |
| SCHEMBL14290316 | 0.84 | NR1H4 (0.73) | TNFRSF1AMAPTLMNAHTTATM | |
| SCHEMBL30307316 | 0.83 | POLB (0.78) | TNFRSF1AMAPTLMNAHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034413-A2 | METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-03-09 | — | — | WO | claimed |
| WO-2023034413-A2 | METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-03-09 | — | — | WO | disclosed |