Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | LMNA | P02545 | 4/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | ATM | Q13315 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.72 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1797256 | 1.00 | MAPT (0.73) | MAPTLMNAHTTATMHPGD | |
| SCHEMBL14290316 | 0.91 | NR1H4 (0.73) | MAPTLMNAHTTATMHPGD | |
| SCHEMBL16211003 | 0.88 | TNFRSF1A (0.78) | MAPTLMNAHTTATMHPGD | |
| SCHEMBL30307308 | 0.88 | TNFRSF1A (0.78) | MAPTLMNAHTTATMHPGD | |
| SCHEMBL16211002 | 0.88 | TNFRSF1A (0.78) | MAPTLMNAHTTATMHPGD | |
| SCHEMBL1799934 | 0.87 | TNFRSF1A (0.78) | MAPTLMNAHTTATMHPGD | |
| SCHEMBL1799936 | 0.87 | TNFRSF1A (0.78) | MAPTLMNAHTTATMHPGD | |
| SCHEMBL15619200 | 0.81 | MAOB (0.72) | MAPTLMNAHTTATMHPGD | |
| SCHEMBL15619199 | 0.81 | MAOB (0.72) | MAPTLMNAHTTATMHPGD | |
| SCHEMBL1285839 | 0.80 | MAPT (0.67) | MAPTLMNAHTTATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951827-B2 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2011-05-31 | — | — | US | disclosed |
| US-20060264487-A1 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | TIDWELL RICHARD R | 2006-11-23 | — | — | US | disclosed |
| EP-1719767-A1 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | The University of North Carolina at Chapel Hill (US) | 2006-11-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264487-A1 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | PFAS, DHPS, DDO | MAPT 3997/4885LMNA 1692/4885HTT 3838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.