SCHEMBL16211003

SCHEMBL16211003

COc1ccc(Br)cc1C=CC(=O)c1ccc(OC)c(OC)c1

nearest known ligand 0.78

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TNFRSF1A P19438 6/20 0.78
▸ MAPT P10636 3/20 0.70
▸ LMNA P02545 2/20 0.70
▸ HTT P42858 2/20 0.70
▸ ATM Q13315 2/20 0.70
▸ MEN1 O00255 1/20 0.70
▸ MITF O75030 1/20 0.70
▸ ALDH1A1 P00352 1/20 0.70
▸ KMT2A Q03164 1/20 0.70
▸ PAX8 Q06710 1/20 0.70
▸ SMN1; SMN2 Q16637 1/20 0.70
▸ NPSR1 Q6W5P4 1/20 0.70
▸ ABCG2 Q9UNQ0 6/20 0.65
▸ MAOB P27338 1/20 0.63
▸ ABCB1 P08183 2/20 0.62
▸ HPGD P15428 1/20 0.61
▸ CAPN1 P07384 1/20 0.60
▸ DPP4 P27487 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16211002 1.00 TNFRSF1A (0.78) TNFRSF1AMAPTLMNAHTTATM
SCHEMBL30307308 1.00 TNFRSF1A (0.78) TNFRSF1AMAPTLMNAHTTATM
SCHEMBL1799936 0.92 TNFRSF1A (0.78) TNFRSF1AMAPTLMNAHTTATM
SCHEMBL1799934 0.92 TNFRSF1A (0.78) TNFRSF1AMAPTLMNAHTTATM
SCHEMBL1797256 0.88 MAPT (0.73) TNFRSF1AMAPTLMNAHTTATM
SCHEMBL1797257 0.88 MAPT (0.73) TNFRSF1AMAPTLMNAHTTATM
SCHEMBL19468567 0.84 ABCG2 (0.86) TNFRSF1AMAPTLMNAATMSMN1; SMN2
SCHEMBL16181498 0.84 ABCG2 (0.67) TNFRSF1AMAPTLMNAATMMEN1
SCHEMBL14290316 0.84 NR1H4 (0.73) TNFRSF1AMAPTLMNAHTTATM
SCHEMBL30307316 0.83 POLB (0.78) TNFRSF1AMAPTLMNAHTTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240366586-A1 METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-11-07 — — US claimed
WO-2023034413-A2 METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-03-09 — — WO claimed
US-20240366586-A1 METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-11-07 — — US disclosed
US-9796676-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2017-10-24 — — US disclosed
US-20160251312-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2016-09-01 — — US disclosed
US-9357781-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2016-06-07 — — US disclosed
US-20140329674-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2014-11-06 — — US disclosed
WO-2014179785-A1 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF INSCENT, INC. (US) 2014-11-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160251312-A1 Honeybee Repellents and Uses Thereof ACHE, AHNAK, L3MBTL3 TNFRSF1A 4228/4885MAPT 1877/4885LMNA 4114/4885
US-20240366586-A1 METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE IL15, IL2, IL17A TNFRSF1A 315/4885MAPT 1073/4885LMNA 4368/4885
US-20140329674-A1 Honeybee Repellents and Uses Thereof ACHE, AHNAK, L3MBTL3 TNFRSF1A 4228/4885MAPT 1877/4885LMNA 4114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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