SCHEMBL30307404

SCHEMBL30307404

CC(CC1=CC([Si](C)(C)Cl)c2ccccc21)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
AOC3 Q16853 2/20 0.35
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
MAOA P21397 3/20 0.35
MAOB P27338 3/20 0.35
NISCH Q9Y2I1 3/20 0.35
P2RX7 Q99572 2/20 0.35
TAAR1 Q96RJ0 5/20 0.34
TRPA1 O75762 1/20 0.31
RIPK1 Q13546 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20996649 1.00 ALDH1A1 (0.36) ALDH1A1AOC3MEN1POLBKMT2A
SCHEMBL20996642 0.89 ALDH1A1 (0.38) ALDH1A1AOC3MEN1POLBKMT2A
SCHEMBL30307383 0.89 ALDH1A1 (0.38) ALDH1A1AOC3MEN1POLBKMT2A
SCHEMBL21029472 0.86 ALDH1A1 (0.36) ALDH1A1MEN1POLBKMT2AATM
SCHEMBL30307378 0.83 P2RX7 (0.35) ALDH1A1MEN1POLBKMT2AATM
SCHEMBL20996648 0.83 P2RX7 (0.35) ALDH1A1MEN1POLBKMT2AATM
SCHEMBL20996646 0.82 P2RX7 (0.34) ALDH1A1MEN1POLBKMT2AATM
SCHEMBL20996633 0.80 MAOA (0.32) ALDH1A1MAOAMAOBNISCHP2RX7
SCHEMBL28894343 0.78 P2RX7 (0.32) ALDH1A1P2RX7
SCHEMBL28425126 0.77 MEN1 (0.38) ALDH1A1AOC3MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111406078-B Catalyst for preparing polyethylene with broad bimodal molecular weight distribution 埃克森美孚化学专利公司 2023-03-10 CN disclosed