SCHEMBL3030855

SCHEMBL3030855

Clc1ccc(-n2ccnc2-c2ccccc2)cc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK9 P45984 1/20 0.55
MAPK10 P53779 1/20 0.55
TSHR P16473 1/20 0.52
KDR P35968 11/20 0.50
SMN1; SMN2 Q16637 1/20 0.43
RAD51 Q06609 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
GAA P10253 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
HTT P42858 1/20 0.42
RPA1 P27694 1/20 0.42
NOTUM Q6P988 1/20 0.41
FLT1 P17948 2/20 0.40
FLT4 P35916 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23903509 0.83 MAPK9 (0.51) MAPK9MAPK10TSHRKDRMAOA
SCHEMBL23884827 0.83 MAPK9 (0.48) MAPK9MAPK10TSHRKDRSMN1; SMN2
SCHEMBL28302004 0.82 MAPKAPK2 (0.53) MAPK9MAPK10KDRKDM4EALDH1A1
Benzene SCHEMBL27839441 0.79 MAPK9 (0.54) MAPK9MAPK10KDRSMN1; SMN2CYP1A2
SCHEMBL528245 0.79 MAPK9 (0.54) MAPK9MAPK10KDRSMN1; SMN2CYP1A2
SCHEMBL25442750 0.79 MAPK9 (0.56) MAPK9MAPK10KDRMAOAMAOB
SCHEMBL15315972 0.79 MAPK10 (0.83) MAPK9MAPK10KDRMAOAMAOB
Hydrochloric Acid SCHEMBL27683877 0.78 MAPK9 (0.53) MAPK9MAPK10KDRSMN1; SMN2CYP1A2
SCHEMBL15315973 0.77 MAPK9 (0.53) MAPK9MAPK10KDRMAOAMAOB
SCHEMBL10900906 0.77 ALDH1A1 (0.51) SMN1; SMN2MAOAMAOBALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1886759-B1 WATER-SOLUBLE PREFLUX AND USE THEREOF SHIKOKU CHEM (JP) 2016-10-05 EP disclosed
US-7754105-B2 Water-soluble preflux and usage of the same SHIKOKU CHEMICALS CORPORATION (JP) 2010-07-13 US disclosed
US-20080318070-A1 Water-Soluble Preflux and Usage of the Same SHIKOKU CHEMICALS CORPORATION (JP) 2008-12-25 US disclosed
EP-1886759-A1 WATER-SOLUBLE PREFLUX AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2008-02-13 EP disclosed