SCHEMBL30309217

SCHEMBL30309217

N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 13/20 0.57
▸ NPY1R P25929 8/20 0.57
▸ NPY2R P49146 6/20 0.57
▸ NPY5R Q15761 6/20 0.57
▸ IL23R Q5VWK5 3/20 0.50
▸ CHRNA1 P02708 1/20 0.47
▸ CHRNG P07510 1/20 0.47
▸ CHRNB1 P11230 1/20 0.47
▸ CHRND Q07001 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29757876 0.92 NPY4R (0.57) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL30901129 0.91 NPY4R (0.62) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29932214 0.90 NPY4R (0.63) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29483767 0.90 NPY4R (0.68) NPY4RNPY1RNPY2RNPY5RCHRNA1
SCHEMBL29625340 0.90 NPY4R (0.63) NPY4RNPY1RNPY2RNPY5RCHRNA1
SCHEMBL7119638 0.90 NPY4R (0.63) NPY4RNPY1RNPY2RNPY5RCHRNA1
SCHEMBL29641074 0.90 NPY4R (0.63) NPY4RNPY1RNPY2RNPY5RCHRNA1
SCHEMBL30608889 0.90 NPY4R (0.63) NPY4RNPY1RNPY2RNPY5RCHRNA1
SCHEMBL30036967 0.90 NPY4R (0.68) NPY4RNPY1RNPY2RNPY5RCHRNA1
SCHEMBL30143658 0.90 NPY4R (0.63) NPY4RNPY1RNPY2RNPY5RCHRNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11612633-B2 Methods and compositions for preventing or treating ophthalmic conditions STEALTH BIOTHERAPEUTICS INC. (US) 2023-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11612633-B2 Methods and compositions for preventing or treating ophthalmic conditions CRYAA, CRYAB, IAPP NPY4R 379/4885NPY1R 144/4885NPY2R 198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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