Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898011 | 1.00 | IDO1 (0.42) | IDO1MEN1KMT2APOLBLMNA | |
| SCHEMBL26931383 | 0.83 | MAPT (0.36) | MEN1KMT2ASMN1; SMN2GAAFPR3 | |
| SCHEMBL26931434 | 0.82 | FPR3 (0.35) | IDO1SMN1; SMN2FPR3FPR2NPC1 | |
| SCHEMBL21598663 | 0.81 | ALDH1A1 (0.42) | IDO1MEN1KMT2APOLBLMNA | |
| SCHEMBL30254359 | 0.81 | ALDH1A1 (0.42) | IDO1MEN1KMT2APOLBLMNA | |
| SCHEMBL21608246 | 0.79 | RORC (0.44) | IDO1MEN1KMT2APOLBLMNA | |
| SCHEMBL30004261 | 0.79 | SYK (0.44) | RORC | |
| SCHEMBL25898751 | 0.79 | SYK (0.44) | RORC | |
| SCHEMBL22288600 | 0.77 | SMN1; SMN2 (0.50) | MEN1KMT2ALMNASMN1; SMN2RORC | |
| SCHEMBL26945253 | 0.76 | MAPT (0.36) | MEN1KMT2ALMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161641-A1 | LPA RECEPTOR ANTAGONISTS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-04-12 | — | — | EP | disclosed |
| CN-115942972-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-04-07 | — | — | CN | disclosed |