Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30311892 | 0.90 | MAPK1 (0.50) | KDM4ECYP11B1CYP11B2PDGFRBMKNK1 | |
| SCHEMBL31464887 | 0.84 | KDM4E (0.51) | HTTKDM4ELMNAMKNK1MKNK2 | |
| SCHEMBL25463116 | 0.84 | LMNA (0.51) | HTTKDM4ELMNAMKNK1MKNK2 | |
| SCHEMBL20255018 | 0.76 | LMNA (0.46) | HTTKDM4ELMNACYP11B1CYP11B2 | |
| SCHEMBL29688687 | 0.76 | LMNA (0.46) | HTTKDM4ELMNACYP11B1CYP11B2 | |
| SCHEMBL31591514 | 0.75 | POLB (0.50) | HTTKDM4ELMNACYP11B1CYP11B2 | |
| SCHEMBL20118972 | 0.75 | KDM4E (0.53) | HTTKDM4ELMNACYP11B1CYP11B2 | |
| SCHEMBL13187708 | 0.73 | CSF1R (0.41) | — | |
| SCHEMBL29933487 | 0.72 | MKNK1 (0.55) | CYP11B1CYP11B2MKNK1MKNK2MAPK1 | |
| SCHEMBL20118977 | 0.72 | NPC1 (0.53) | HTTKDM4ELMNAMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867542-B | Novel benzimidazole compound | 微境生物医药科技(上海)有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-115867542-A | Novel benzimidazole compounds | 微境生物医药科技(上海)有限公司 | 2023-03-28 | — | — | CN | disclosed |