Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188472 | 0.90 | MAPT (0.42) | CSF1RPDE10AAAK1ABCB1ABCC1 | |
| SCHEMBL3709739 | 0.88 | MEN1 (0.41) | CSF1RFFAR1MMP1MMP9MMP13 | |
| SCHEMBL13187704 | 0.87 | NPC1 (0.44) | CSF1RMMP1MMP9MMP13ADAM17 | |
| SCHEMBL3713434 | 0.85 | GRM5 (0.48) | CSF1RGRM5ERN1FFAR1MMP13 | |
| SCHEMBL3712228 | 0.84 | ABCB1 (0.38) | CSF1RGRM5AAK1ABCB1ABCC1 | |
| SCHEMBL13188481 | 0.84 | PTGES (0.42) | CSF1RERN1FFAR1MMP1MMP9 | |
| SCHEMBL13188838 | 0.84 | MAPT (0.40) | CSF1RGRM5AAK1 | |
| SCHEMBL13188547 | 0.84 | MCL1 (0.47) | — | |
| SCHEMBL3709730 | 0.78 | PLA2G2A (0.44) | FFAR1AAK1 | |
| SCHEMBL13188626 | 0.77 | AAK1 (0.44) | CSF1RERN1FFAR1MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |